A groundbreaking fluorescent material, Ph-Cys-Au, has emerged, crafted from phosphorene, cystine, and gold. It boasts exceptional optical traits, primed for detecting Methotrexate, a prevalent anti-cancer medication. This innovative substance showcases remarkable properties owing to its unique composition. Researchers have harnessed phosphorene, cystine, and gold to engineer this cutting-edge material, offering promising advancements in drug overdose detection. Its impressive fluorescence capabilities pave the way for swift and accurate Methotrexate identification, setting a new standard in medical detection methods.

A groundbreaking substance, Ph-Cys-Au, with outstanding optical traits emerges. Crafted from phosphorene, cystine, and gold, it’s a high-fluorescence marvel. Its purpose? Detecting Methotrexate, a widely-used anti-cancer drug. An excess of MTX is harmful, impacting lungs, stomach, and heart. This material offers a visual sensing platform. By utilizing its exceptional properties, it identifies MTX efficiently. The development of Ph-Cys-Au marks a significant leap in drug detection technology, ensuring quicker and more precise identification of potential overdoses.

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Monitoring drug effects is crucial; they can harm the body. An MTX level above 10 µM in plasma for over 10 hours is risky. MTX is costly, and overdose detection is slow and complex. Addressing these concerns, we need quick, sensitive detection methods. Fast, simple techniques are necessary due to these issues in detecting drug overdose, especially considering the high expense and potential dangers of prolonged presence in the body.

Scientists at the Institute of Advanced Study in Science and Technology (IASST), a part of the Department of Science and Technology (DST), tackled this issue. Their team, led by Professor Neelotpal Sen Sarma and Dr. Mojibur R Khan, along with scholars Nasrin Sultana and Chingtham Thanil Singh, created Ph-Cys-Au. This remarkable material possesses exceptional optical properties, serving as a visual sensor for detecting MTX. According to a press release, this non-enzymatic method aids in analyzing therapeutic cytotoxicity related to the anti-cancer drug Methotrexate.

According to the release, this sensing platform surpasses previous systems. The materials used are biocompatible, boasting a notable detection limit.

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